A New Look at MicroRNA

September 25, 2014

I have just completed a report for Kalorama on microRNAs, a unique classof  non-coding RNA molecules. These are members of the class of non-translated molecules that do NOT produce protein. They are small, single-stranded fragments (19-30 nucleotides long) that serve widespread functions as regulatory molecules in post-transcriptional gene silencing. They are now recognized as pivotal regulators of gene expression; including development, proliferation, differentiation, and apoptosis.

Recently discovered, their origins go back only to the 1990s. Nonetheless, they have engendered great enthusiasm due to their critical role in regulatory control and their resulting significance as biomarkers and subjects of therapeutic intervention.

The report will be available shortly. I recommend it to your attention.

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