Epigenetic Publications Surge

March 1, 2013

As I noted in my report on Epigenetics, published by Kalorama in 2012, the field is on the cusp of an explosion, which is now taking place.  According to an assessment in Genetic Engineering and Biotechnology News (http://www.genengnews.com/gen-articles/en-bloc-analysis-of-b-epigenetic-b-b-publications-b/4704/), publications are proliferating at an exponential rate, particularly in the field of cancer research. The authors also claim that other epigenetic-based disease research areas are expanding rapidly, including cardiovascular, neurological and obesity targeted investigations.

The authors retrieved 28,000 publications on epigenetics-related topics from a Medline search. Examples of this publication tsunami are already translating into drugs approvals (currently six) or into clinical trials , with much of the effort in oncology. Because model of epigenetic mechanisms in other areas are not far advanced, we can anticipate that translational research in these areas will proceed more slowly, but nonetheless will soon ramp up.

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